Latest News:


  1. -3/2009: Our new facility, the Cornell Biofuels Research Lab was
    officially completed. Read about it here.

  2. -12/2008: Our study o
    n binding of cellulases on immobilized cellulose fibrils was featured on the cover of Biotechnology and Bioengineering:
  3.  

  4. -12/2008: Congratulations to Linelle Fontenelle for passing her A exam!


  5. -10/2008: Congratulations to Sarah Munro for passing her A exam!


  1. -7/2008: Congratulations to Jeremy Luterbacher for passing his Q exam!

 

Dear Visitor,


    Welcome to the Biomass Conversion Laboratory website.   Our research and education activities are primarily focused on industrial biotechnology solutions to energy and environmental challenges.  We very much enjoy exploring research problems that are at the interface between biological and physical sciences.  Our success in exploring these problems hinges on the strong collaborative relationships that we have established with molecular biologists, microbiologists, plant biologists, systems biologists, applied physicists and material scientists.  It is through these collaborative relationships that we are able to develop new methods and evolve new research paradigms.  Many of the research projects and results that are presented on this website reflect on the contribution of our collaboration, and they capture the
commitment of our broader team to addressing energy and  environmental challenges through science and engineering. In addition, many of the projects involve empirical and mathematical modeling to glean insights into industrial biotechnology problems.



  

 
    A core element of our success in exploring and addressing research problems at the interface of  biological and physical sciences is having access to state-of-the-art research facilities.  Many of the projects described in this web-site are being facilitated by Cornell’s Biofuels Research Laboratory (BRL) – which contains 11,500 square feet of space in the East Wing of Riley-Robb Hall.  The BRL was designed and built to address biological barriers to the development of cellulosic biofuels such as ethanol, butanol, hydrogen and methane. Within the walls of this laboratory are ten different facilities designed to enhance our ability to address physical, chemical and biological barriers to liberating sugars from energy crops, such as switchgrass, cold tolerant sorghum, and woody biomass, and to biologically convert these sugars into biofuels.  There is an advanced imaging laboratory to carry-out single molecule studies of cellulases and other plant cell wall degrading enzymes, robotics platforms for high-throughput screening of microorganisms and enzyme cocktails, analytical equipment such as LC-MS, FPLC
and FTNIR for measuring and purifying secondary metabolites and assessing chemical compositions of biomass streams, and a number of thermochemical reactors for pretreating biomass material and for microbial conversion.  In addition, there is office space designed to accommodate researchers from different disciplines that are part of our broader biofuels community, and to provide the environment for them to share research methods, insights and perspective, which is essential for multidisciplinary research projects.



    Another essential characteristic of the Biomass Conversion laboratory is the “systems” perspective that each member brings to energy and environmental problems.  There are a number of different ways that advanced biotechnological, chemical and physical processes can be coupled together to form “industrial ecologies” – to integrate an entire industrial process to determine maximal beneficial use of resources, optimize the utilization of the resource, minimize waste generation during the obtaining and processing of the resource, minimize waste during manufacturing, maximize destruction or reuse of waste resulting from manufacturing, maximize the ultimate recycling or disposal of the product, and minimize consumption of energy throughout the process. Many of the attributes exhibited by an “industrial ecology” can be found in microbial systems and the field of “systems biology” has evolved to capture these attributes through in-silica modeling of metabolic and signaling pathways.  Thus, there are members of the Biomass conversion laboratory who are integrating systems biology tools into our research activities, and others are performing input/output modeling and life cycle analysis of biobased industries.  The goal is to strengthen our ability to develop sustainable biobased industries through good science and engineering and systems thinking.


    Thank you for taking time to visit our website.  We hope that this time was well spent.


Best regards,








L. P. Walker, Ph.D.

Professor